• 22 Feb, 2025

New England Biolabs® to Present Latest Innovations in Next Generation Sequencing Sample Preparation at AGBT 2025

New England Biolabs® to Present Latest Innovations in Next Generation Sequencing Sample Preparation at AGBT 2025

Data will be presented on new and upcoming technologies, including fast, streamlined library preparation, plus new technologies for epigenetics and new sequencing platforms.

IPSWICH, Mass., Feb. 21, 2025 -- New England Biolabs (NEB®) will be presenting a host of technologies aimed at streamlining sample preparation technologies towards the production of high-quality sequencing data at this year's Advances in Genome Biology and Technology (AGBT) General Meeting.

Specifically, NEB will share details and experiences around the recently released NEBNext® Enzymatic Methyl-seq v2 kit, which expands the dynamic input range for the technology down to 100 picograms of DNA mass, rendering it applicable for a wide range of applications across general and clinical research utilities.

Additionally, presentations will feature streamlined workflows to prepare samples from cell-free DNA and RNA, including Monarch® bead-based extraction, through to library preparation using NEBNext Ultra II and UltraExpress® DNA and RNA kits. These workflows offer substantial time and efficiency savings, enabling high-quality data from diminishing sample inputs.

NEB will also share details on the expanded NEBNext portfolio for epigenetics studies, including the adapted Enzymatic 5hmC-seq Kit for detection of 5hmC, as well as new technologies for enzymatic DNA fragmentation, chromatin structure analysis and improvements in data analysis.

This year's meeting will be held from February 23 - 26, in Marco Island, Florida, and NEB's base will be the Osprey 5 Suite.

Presentations:

Epigenetic Analysis Then and Now 

Ivo Glynne Gut, Ph.D. Director, Centro Nacional de Analisis
Genomico, Barcelona, Spain

 

Bronze Sponsor Workshop

 

Wednesday, 3:00 PM, Calusa Ballroom

Novel NEBNext Solutions for
Epigenetics: EM-seq v2, E5hmC-
seq, and UltraShear Fragmentation
 

  • EM-seq v2, E5hmC-seq

  • UltraShear enzymatic DNA
    fragmentation

Louise Williams, Ph.D., Sr. Manager, NGS Development

 

V.K Chaithanya Ponnaluri, Ph.D. Manager NGS
Development 

 

Monday, 8:00-8:30 AM, Osprey 5 

Streamlined for speed: NEBNext
UltraExpress DNA and RNA library
prep
 

 

(Bonus: Find out why the next big
thing in RNA is small!)
 

 

  • Streamlined DNA and RNA
    sample preparation workflows

  • Updates on a new Low-bias
    Small RNA kit

Chen Song, Ph.D., Manager NGS Development 

 

Louise Williams, Ph.D., Sr. Manager, NGS Development 


Wednesday, 8:00 – 8:30 AM, Osprey 5

A number of posters will be presented during the conference and also displayed in Osprey 5. There will be several opportunities to meet with our Development Scientists and learn about NEB's latest technology advances.

Conference posters focusing on our new streamlined library prep workflows for DNA and RNA, and our recently released epigenetics solutions will be presented on Tuesday, 2/25, 4:45-6:10 p.m.

NEB is also a proud sponsor of the Women's Networking event at AGBT.

For more information on the NEBNext portfolio of reagents for sample preparation, visit www.NEBNext.com

About New England Biolabs
For over 50 years, New England Biolabs (NEB) has pioneered the discovery and production of innovative products tailored for molecular biology research. Our commitment to scientific discovery is evident in all that we do, including our ever-expanding product portfolio, investment in our basic and applied research program, and support of customers' research in academia and industry, including cutting-edge technologies for use in molecular diagnostics and nucleic-acid vaccines development. Guided by our founding principles, NEB proactively invests in efforts to improve the well-being of our employees, surrounding communities, as well as the future of our planet. NEB remains a privately held company with global reach, supported by our headquarters in Ipswich, MA, USA, subsidiary offices in 10 countries, and over 60 distribution partners around the world. For more information about New England Biolabs, visit www.neb.com.

NEW ENGLAND BIOLABS®, NEB® and NEBNEXT® and ULTRAEXPRESS® are registered trademarks of New England Biolabs, Inc. EM-SEQ™ and 5HMC-SEQ are trademarks of New England Biolabs, Inc. AGBT™ is a trademark of The Genome Partnership.

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