SAN DIEGO, April 29, 2025 -- Huxley Medical unveiled promising investigational data from the company's SANSA monitoring platform at the Heart Rhythm Society meeting, held in San Diego from April 24-27. In the observational study, investigators evaluated the feasibility of SANSA to simultaneously assess sleep apnea, arrhythmia, and activity patterns. The study highlights the high burden of unrecognized sleep apnea in electrophysiology populations and the breadth of insights the SANSA multi-sensing platform is capable of generating from a single use. With continued development, researchers believe SANSA could simplify diagnostic workflows for complex patients and enhance cross-specialty collaboration between cardiology, electrophysiology, and sleep medicine.
Key findings from the research:
- Previously unrecognized sleep apnea was detected in 67% (20/30) of electrophysiology patients being monitored for arrhythmias
- SANSA revealed sleep apnea during a daytime nap as well as overnight sleep, highlighting how typical overnight-only home sleep apnea testing may miss the full burden of disease and not capture valuable information about patients' circadian sleep patterns
- Simultaneous collection of ECG alongside oximetry, motion, and respiration provided valuable context to understand relationships between arrhythmia burden, sleep, and activity level
The research team leading the study suggested that unifying the assessment of sleep-disordered breathing and cardiac arrhythmias could provide valuable insight into disease states and inform clinical management of complex patients. Rohit Mehta, MD, cardiac electrophysiologist at the Sanger Heart and Vascular Institute and Professor of Medicine at Wake Forest University School of Medicine, said, "A key unmet need in current diagnostic assessments is the ability to contextualize when disease occurs and to identify how different disease states influence one another. This is particularly true for frequently comorbid conditions like various arrhythmias and sleep apnea. A unified assessment could help tailor disease management for the patient and allow more specific and appropriate therapies to be provided. This study suggests promising potential for SANSA to help address this need and motivates continued clinical research and validation."
Samuel Sears, PhD, ABPP, professor of cardiovascular sciences and psychology at East Carolina University and division chief of innovation and research for the East Carolina Heart Institute, added "Keeping patients active and understanding how their heart responds to physical activity is one of the most critical things we can do for our cardiac patients. Devices like SANSA that provide this level of information alongside standard Holter data could become the standard."
Researchers also highlighted the promise of SANSA to streamline workflows and strengthen how different clinical specialties work together to provide care. Douglas Kirsch, MD, Medical Director of Sleep Medicine at Atrium Health and Clinical Professor of Neurology at Wake Forest University School of Medicine, said, "Siloed workflows create complexity for patients and hamper inter-specialty collaboration. Devices with muti-diagnostic capabilities, like SANSA, may enable faster and more efficient approaches to patients where both sleep and cardiac disorders are suspected."
About Huxley Medical
Huxley Medical, Inc. is a privately held medical technology company on a mission to develop diagnostic solutions that streamline care for any patient anywhere. The company has received funding from the National Science Foundation, National Institutes of Health, Georgia Research Alliance Venture Fund, Invest Georgia, Georgia Tech Foundation Research Impact Fund, and Duke Capital Partners to translate its growing technology portfolio. To learn more, visit huxleymed.com or email info@huxleymed.com.
Research abstract: "Simultaneously Monitoring Patterns of Arrhythmia, Sleep Apnea, and Activity with a Single Chest-worn Device"
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